منابع مشابه
Toxicokinetics of Kava
Kava is traditionally consumed by South Pacific islanders as a drink and became popular in Western society as a supplement for anxiety and insomnia. Kava extracts are generally well tolerated, but reports of hepatotoxicity necessitated an international reappraisal of its safety. Hepatotoxicity can occur as an acute, severe form or a chronic, mild form. Inflammation appears to be involved in bot...
متن کاملKava lactones and the kava-kava controversy.
Kava-kava is a traditional beverage of the South Pacific islanders and has had centuries of use without major side effects. Standardised extracts of kava-kava produced in Europe have led to many serious health problems and even to death. The extraction process (aqueous vs. acetone in the two types of preparations) is responsible for the difference in toxicity as extraction of glutathione in add...
متن کاملKava kava: examining new reports of toxicity.
Before 1998, extracts of kava kava, Piper methysticum, were considered to be very safe alternatives to anxiolytic drugs and to possibly exert a wide range of other benefits. Major reviews published through the end of 2002 continued to confirm kava's safety and efficacy. Nevertheless, by January 2003 kava extracts had been banned in the entire European Union and Canada, and were subject to cauti...
متن کاملPiper methysticum (kava kava) Monograph
Description and Constituents Piper methysticum (kava kava) is a perennial plant native to the Pacific Island region, and has been used ceremonially for thousands of years. Traditionally, a beverage is prepared, then drunk before the evening meal. Indigenous methods of mastication of the kava root have given way to grinding or pounding the plant substance, which is then mixed with water or cocon...
متن کاملKava-Kava and Liver Toxicity Concerns
How Did These Concerns Start? The German Federal Institute for Drugs and Medical Devises allegedly discovered 24 cases of liver toxicity associated with kava use. Switzerland has reported 5 cases. Diagnoses included hepatitis, cirrhosis, and liver failure. Switzerland has banned products containing the kava extract, while German authorities have proposed to follow suit. Now health authorities a...
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ژورنال
عنوان ژورنال: Advances in Pharmacological Sciences
سال: 2011
ISSN: 1687-6334,1687-6342
DOI: 10.1155/2011/326724